With some common goals, such as relieving symptoms and complications cancer-relat, preventing and rucing treatment-relat toxicities, improving tolerance to therapy, improving communication tween patients and health personnel, rucing the emotional burden tween patients and caregivers, and optimizing the care of survivors. Within geriatric syndromes, some of them are associat with worse results in some cancer treatments. Frailty is defin as a cyclical, complex, and multidimensional state of ruction of the physiological reserve, resulting in a lower capacity for resilience, adaptation, and increas vulnerability to stressors. In the general TH Lists population, its prevalence varies tween 10% and 20% among people older than 65 years.