The geriatrician dicat to evaluating and supporting cancer patients, known today as an oncogeriatrician, uses different tools and instruments to perform a comprehensive geriatric report, subdividing patients according to a greater or minor risk of toxicities to therapies and according to the objective expectations of survival with or without systemic treatment, allowing a rational take of decisions (Mohile et al., 2013). Characteristics of elderly cancer patients Older people are a group with special characteristics, very different when compar to the younger population. Therefore, it is important to establish some concepts to clarify the differences tween geriatrics and non-geriatric adult patients. Briefly, we will explain physiological changes, and geriatric syndromes which include but are not limit to frailty, polypharmacy, and its consequences, fall syndrome, and malnutrition in the elderly and their relationship with cancer treatments.
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There are important physiological changes in the aging process. Knowing the heterogeneity of physiological changes in pharmacokinetics, pharmacodynamics, tolerance in different tissues, and how this influences carcinogenesis is essential for understanding the link tween cancer and its treatment in older people. Vulnerabilities Chad Email List assessment, the presence or absence of frailty, and comorbidities are associat with life expectancy (Williams et al., 2016; Balducci and Extermann, 2000). The objectives in the management of elderly patients with cancer should individualiz according to the context of each person as an individual.
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With some common goals, such as relieving symptoms and complications cancer-relat, preventing and rucing treatment-relat toxicities, improving tolerance to therapy, improving communication tween patients and health personnel, rucing the emotional burden tween patients and caregivers, and optimizing the care of survivors. Within geriatric syndromes, some of them are associat with worse results in some cancer treatments. Frailty is defin as a cyclical, complex, and multidimensional state of ruction of the physiological reserve, resulting in a lower capacity for resilience, adaptation, and increas vulnerability to stressors. In the general TH Lists population, its prevalence varies tween 10% and 20% among people older than 65 years.