The prevalence of frailty report among cancer patients ranges from 6% to 86%, with a mian of 42% (Handforth et al., 2015). Frailty is associat with a worse survival rate with an HR 2.67 (95% CI 1.11–6.83, p0.029) according to the Linda Fri Frailty phenotype, increasing to an HR 3.39 (95% CI 1.82–6.29, p < 0.001) when it is diagnos by a comprehensive geriatric assessment (Kristjansson et al., 2010). It is also associat with a higher incidence of colorectal postsurgical complications with an OR 4.083 (95% CI 1.4–11.6, p0.006) (Tan et al., 2012) and in gastric surgery with an increase in systemic complications, OR 6.06 (95% CI 1.78–20.9, p0.004) (Lu et al., 2017). Report frailty among the Chilean elderly population, bas on analysis from the Chilean National Health System, accounts for 10.9% for males and 14.1% for females respectively.
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Depending on the associat morbidity report frailty 0% when no comorbidity exists, 6.2% when only one comorbidity is present, but it raises to 64% when three or more comorbidities are present. 32.6% of cancer patients are frail according to this report (Troncoso-Pantoja et al., 2020). One of the major problems in geriatrics is Chile Email List polypharmacy (Whitman et al., 2018). There is no consensus for a clear definition for this term (Masnoon et al., 2017), then we could assume that the concomitant use of two or more drugs could includ within this definition. Some authors such as Turner consider polypharmacy when a patient uses five or more different drugs (Turner et al., 2014). Polypharmacy has en associat with a greater probability of interrupting schul surgery (Parks et al., 2015), an increase in almost double the risk of post-surgical complications.
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A greater ne for hospitalizations (Badgwell et al., 2013), and an increase of six times more grade three or greater chemotoxicities (Hamaker et al., 2014). Polypharmacy is also responsible for producing greater functional deterioration, a higher incidence of delirium (Şenel et al., 2017), and an almost 10-fold increase in the 30-day mortality days in select populations (Elliot et al., 2014). Another important geriatric syndrome to consider and prevent is the “fall syndrome”. The current presence or a previous history of cancer increases the risk of falls by 15%–20% (Mohile et al., 2011). It is essential to ask about the antecent of falls during the last 6 months, as TH Lists well as the limitations in activities of daily living, cancer-relat fatigue, to assess walking and balance disorders, to request vitamin D plasmatic levels.
